Most techniques utilize membranes, which are inserted over the bone defects. Most of these membranes are bio-absorbable, and do not require removal. Other regenerative procedures involve the use of bioactive gels, proteins, peptides, etc., to stimulate new bone formation.
GEM 21S
FDA Clinical Trial
The safety and efficacy of GEM 21S® Growth-factor Enhanced Matrix has been evaluated in the most extensive, prospective, randomized, controlled, blinded clinical trial conducted for a regenerative product in dentistry.
The study was a large, multicenter study involving 180 patients and 11 clinical sites (4 universities and 7 private practices.)
Periodontal regeneration is defined as the formation of new bone, new cementum and new periodontal ligament to form a functional attachment apparatus on a previously pathologically exposed tooth root.
This has long been the goal of periodontal treatment although, until now, it was commonly considered challenging and highly unpredictable by most clinicians.
Clinical data suggests that over tie (approximately 6 months) maturation of cementum, PDL, and supporting alveolar bone occurs.
The end result is enhanced bone and periodontal regeneration.
